We are committed to aiding in the eradication of malaria worldwide. Unlike conventional approaches for developing treatments for humans infected by parasites, our strategy aims to identify therapeutics for malaria and other parasitic diseases by beginning with precise molecular information about how a drug will hinder a parasite. We seek equity in global health by mitigating crises that have long ravaged non-western nations and that now threaten the globe due to transnational travel and alterations in climate.
KAINOMYX SCIENTIFIC PLATFORM
Parasite division, morphogenesis, and host invasion are force-dependent processes
Cytoskeletal filament tracks propelled by force-producing molecular motors attached to a surface
“Watching the filaments move around like glowing worms reminded me that the motion inherent in life, so mysterious to the Greeks and early-twentieth-century researchers alike, was now without doubt explained by the amazing motions of mere molecules.”
“We have come a long way – from the vital forces of the ancients to the molecules of molecular biologists and biophysicists. If we are seeking the ‘life force,’ the force that animates life, then our search has been successful. This animating force is the random force of atoms, the jittering afterglow of the creation of the universe. The molecular machines, which take this undirected force and give it direction, embody the tight embrace of chance and necessity and are themselves the product of this embrace. Sculpted by evolution, the molecular machines of our bodies tame the molecular storm and turn it into the dance of life.”
Peter M. Hoffman, Life’s Ratchet, How Molecular Machines Extract Order from Chaos, published by Basic Books, a member of the Perseus Books Group, 2012.